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Qian Pan Selected Research

Erythrokeratodermia Variabilis

11/2015Pathogenic Cx31 is un/misfolded to cause skin abnormality via a Fos/JunB-mediated mechanism.
1/2012Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell death.
8/2005Intracellular distribution, assembly and effect of disease-associated connexin 31 mutants in HeLa cells.
6/2005Cx31 is assembled and trafficked to cell surface by ER-Golgi pathway and degraded by proteasomal or lysosomal pathways.

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Qian Pan Research Topics

Disease

7Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
02/2014 - 06/2004
6Parkinson Disease (Parkinson's Disease)
02/2013 - 06/2006
4Neoplasms (Cancer)
01/2019 - 12/2004
4Spinocerebellar Ataxias (Spinocerebellar Ataxia)
01/2016 - 10/2008
4Erythrokeratodermia Variabilis
11/2015 - 06/2005
4Hearing Loss (Hearing Impairment)
10/2010 - 06/2005
3Reperfusion Injury
01/2021 - 12/2011
3Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
01/2017 - 06/2005
3Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy)
06/2011 - 10/2008
3Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
12/2008 - 03/2006
2Brain Ischemia (Cerebral Ischemia)
12/2020 - 12/2011
2Autistic Disorder (Autism)
09/2015 - 12/2012
2Norrie disease
05/2015 - 12/2010
2Myopia
04/2015 - 08/2014
2Hereditary Spastic Paraplegia
01/2014 - 01/2004
2Cerebellar Ataxia (Dysmetria)
01/2013 - 02/2006
2Ataxia (Dyssynergia)
06/2012 - 06/2011
2Peripheral Nervous System Diseases (PNS Diseases)
08/2005 - 06/2005
2Retinitis Pigmentosa (Pigmentary Retinopathy)
05/2004 - 04/2003
1Weight Gain
01/2021
1Obesity
01/2021
1Infections
12/2020
1Starvation
11/2019
1Chronic Disease (Chronic Diseases)
01/2019
1Metabolic Diseases (Metabolic Disease)
01/2019
1Autism Spectrum Disorder
04/2016
1Ganglion Cysts (Ganglion)
03/2016
1Skin Diseases (Skin Disease)
11/2015
1Xanthomatosis (Xanthoma)
09/2015
1Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
09/2015
1Mitochondrial Diseases (Mitochondrial Disease)
09/2015
1Necrosis
09/2015
1Hypophosphatemic Rickets
07/2015
1Glioma (Gliomas)
07/2015
1Hyperglycemia
07/2015
1Neuroblastoma
07/2015
1Parkinson Disease 16
04/2015
1Gliosis
07/2014
1Craniofacial Dysostosis (Crouzon Disease)
06/2014
1Multiple System Atrophy
02/2013
1Essential Tremor (Essential Tremors)
02/2013
1Atopic Dermatitis (Atopic Eczema)
07/2012
1Ichthyosis Vulgaris (Dominant Ichthyosis Vulgaris)
07/2012
1Psoriasis (Pustulosis Palmaris et Plantaris)
07/2012
1Diabetic Cardiomyopathies
12/2011
1Cerebral Infarction
12/2011
1Kufor-Rakeb syndrome
08/2011
1Microphthalmos
05/2011

Drug/Important Bio-Agent (IBA)

12Proteins (Proteins, Gene)FDA Link
12/2020 - 01/2004
5human GJB3 proteinIBA
11/2015 - 06/2005
5DNA (Deoxyribonucleic Acid)IBA
06/2012 - 02/2006
4Small Heat-Shock ProteinsIBA
12/2006 - 02/2005
3Nonsense Codon (Nonsense Mutation)IBA
07/2015 - 12/2010
2NucleotidesIBA
12/2020 - 06/2011
2Glucose (Dextrose)FDA LinkGeneric
12/2020 - 11/2019
2UbiquitinIBA
01/2017 - 01/2013
2Glucosylceramidase (Glucocerebrosidase)IBA
02/2013 - 06/2010
2Messenger RNA (mRNA)IBA
12/2011 - 12/2011
2Genetic Markers (Genetic Marker)IBA
05/2011 - 04/2007
2DystrophinIBA
12/2008 - 03/2006
2Codon (Codons)IBA
08/2007 - 10/2005
1Angiotensin-Converting Enzyme 2IBA
01/2021
1LipidsIBA
01/2021
1Anti-Obesity Agents (Antiobesity Drugs)IBA
01/2021
1Triglycerides (Triacylglycerol)IBA
01/2021
1Blood Glucose (Blood Sugar)IBA
01/2021
1Transcription Factors (Transcription Factor)IBA
12/2020
1Oxygen (Dioxygen)IBA
12/2020
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
12/2020
1Polymyxin B (Aerosporin)FDA LinkGeneric
11/2019
1Adenosine Triphosphate (ATP)IBA
11/2019
1CarbonIBA
11/2019
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
01/2019
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
01/2019
1DNA Transposable Elements (Element, IS)IBA
04/2016
1Retinaldehyde (Retinal)IBA
03/2016
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
11/2015
1CholesterolIBA
09/2015
1oxidized low density lipoproteinIBA
09/2015
1Mutant Proteins (Protein, Mutant)IBA
09/2015
1CorticosteroneIBA
07/2015
1Caspase 3 (Caspase-3)IBA
07/2015
1CollagenIBA
04/2015
1Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
04/2015
1HLA-DR Antigens (HLA-DR)IBA
04/2015
1Proteoglycans (Proteoglycan)IBA
07/2014
1GlycosaminoglycansIBA
07/2014
1Dermatan SulfateIBA
07/2014
1Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
06/2014
1Heat-Shock Proteins (Heat-Shock Protein)IBA
02/2014
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2013
1Fragile X Mental Retardation ProteinIBA
12/2012
1Filaggrin ProteinsIBA
07/2012
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
12/2011
1CationsIBA
08/2011
1ManganeseIBA
08/2011
1Ubiquitin Thiolesterase (Ubiquitin Carboxy-Terminal Hydrolase)IBA
04/2011

Therapy/Procedure

2Ligation
01/2014 - 06/2011
2Therapeutics
11/2005 - 12/2004
1Acupuncture Therapy
12/2011